Suppression of Core 1 Gal-Transferase Is Associated with Reduction of TF and Reciprocal Increase of Tn, sialyl-Tn and Core 3 Glycans in Human Colon Cancer Cells

It has long been presumed, though with surprisingly little evidence, a competition between Core 1 Gal-transferase (C1GalT), Core 3 GlcNAc-transferase (C3GnT) and sialyl-transferase (ST6GalNAc-T) for elongation of O-linked mucin-type glycans initiated with GalNAcα-Ser/Thr. This study tested this pres...

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Detalles Bibliográficos
Autores principales: Barrow, Hannah, Tam, Benjamin, Duckworth, Carrie A., Rhodes, Jonathan M., Yu, Lu-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607565/
https://www.ncbi.nlm.nih.gov/pubmed/23536887
http://dx.doi.org/10.1371/journal.pone.0059792

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607565/
https://www.ncbi.nlm.nih.gov/pubmed/23536887
http://dx.doi.org/10.1371/journal.pone.0059792

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