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Assessing the Consequences of Denoising Marker-Based Metagenomic Data
Early marker-based metagenomic studies were performed without properly accounting for the effects of noise (sequencing errors, PCR single-base errors, and PCR chimeras). Denoising algorithms have been developed, but they were validated using data derived from mock communities, in which the true sequ...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607570/ https://www.ncbi.nlm.nih.gov/pubmed/23536909 http://dx.doi.org/10.1371/journal.pone.0060458 |