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Assessing the Consequences of Denoising Marker-Based Metagenomic Data

Early marker-based metagenomic studies were performed without properly accounting for the effects of noise (sequencing errors, PCR single-base errors, and PCR chimeras). Denoising algorithms have been developed, but they were validated using data derived from mock communities, in which the true sequ...

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Detalles Bibliográficos
Autores principales: Gaspar, John M., Thomas, W. Kelley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607570/
https://www.ncbi.nlm.nih.gov/pubmed/23536909
http://dx.doi.org/10.1371/journal.pone.0060458