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Protein Kinase G1 α Overexpression Increases Stem Cell Survival and Cardiac Function after Myocardial Infarction
BACKGROUND: We hypothesized that overexpression of cGMP-dependent protein kinase type 1α (PKG1α) could mimic the effect of tadalafil on the survival of bone marrow derived mesenchymal stem cells (MSCs) contributing to regeneration of the ischemic heart. METHODS AND RESULTS: MSCs from male rats were...
Autores principales: | Wang, Linlin, Pasha, Zeeshan, Wang, Shuyun, Li, Ning, Feng, Yuliang, Lu, Gang, Millard, Ronald W., Ashraf, Muhammad |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607603/ https://www.ncbi.nlm.nih.gov/pubmed/23536905 http://dx.doi.org/10.1371/journal.pone.0060087 |
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