Genetic and Structure-Function Studies of Missense Mutations in Human Endothelial Lipase

Endothelial lipase (EL) plays a pivotal role in HDL metabolism. We sought to characterize EL and its interaction with HDL as well as its natural variants genetically, functionally and structurally. We screened our biethnic population sample (n = 802) for selected missense mutations (n = 5) and ident...

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Detalles Bibliográficos
Autores principales: Razzaghi, Hamid, Tempczyk-Russell, Anna, Haubold, Kurt, Santorico, Stephanie A., Shokati, Touraj, Christians, Uwe, Churchill, Mair E. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607615/
https://www.ncbi.nlm.nih.gov/pubmed/23536757
http://dx.doi.org/10.1371/journal.pone.0055716

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607615/
https://www.ncbi.nlm.nih.gov/pubmed/23536757
http://dx.doi.org/10.1371/journal.pone.0055716

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