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Genetic and Structure-Function Studies of Missense Mutations in Human Endothelial Lipase
Endothelial lipase (EL) plays a pivotal role in HDL metabolism. We sought to characterize EL and its interaction with HDL as well as its natural variants genetically, functionally and structurally. We screened our biethnic population sample (n = 802) for selected missense mutations (n = 5) and ident...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607615/ https://www.ncbi.nlm.nih.gov/pubmed/23536757 http://dx.doi.org/10.1371/journal.pone.0055716 |