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Induction of Potent Antigen-specific Cytotoxic T Cell Response by PLGA-nanoparticles Containing Antigen and TLR Agonist

Previously we showed that biodegradable nanoparticles containing poly-IC or CpG oligodeoxynucleotide (ODN) together with ovalbumin (OVA) were efficient at inducing MHC-restricted presentation of OVA peptides in dendritic cells. The CTL-inducing activities of the nanoparticles were examined in the pr...

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Detalles Bibliográficos
Autores principales: Lee, Young-Ran, Lee, Young-Hee, Kim, Ki-Hyang, Im, Sun-A, Lee, Chong-Kil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Immunologists 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607708/
https://www.ncbi.nlm.nih.gov/pubmed/23559898
http://dx.doi.org/10.4110/in.2013.13.1.30