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Telomerase Reverse Transcriptase (TERT) is a Therapeutic Target of Oleanane Triterpenoid CDDO-Me in Prostate Cancer

Methyl-2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oate (CDDO-Me) is an synthetic oleanane triterpenoid with strong antiprolifertive and proapoptotic activities in cancer cells. However, the effect of CDDO-Me on human telomerase reverse transcriptase (hTERT) and its telomerase activity in prostate canc...

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Detalles Bibliográficos
Autores principales: Liu, Yongbo, Gao, Xiaohua, Deeb, Dorrah, Arbab, Ali S., Gautam, Subhash C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607816/
https://www.ncbi.nlm.nih.gov/pubmed/23519253
http://dx.doi.org/10.3390/molecules171214795