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Components of gating charge movement and S4 voltage-sensor exposure during activation of hERG channels
The human ether-á-go-go–related gene (hERG) K(+) channel encodes the pore-forming α subunit of the rapid delayed rectifier current, I(Kr), and has unique activation gating kinetics, in that the α subunit of the channel activates and deactivates very slowly, which focuses the role of I(Kr) current to...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607828/ https://www.ncbi.nlm.nih.gov/pubmed/23478995 http://dx.doi.org/10.1085/jgp.201210942 |