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A survey of ex vivo/in vitro transduction efficiency of mammalian primary cells and cell lines with Nine natural adeno-associated virus (AAV1-9) and one engineered adeno-associated virus serotype

BACKGROUND: The ability to deliver a gene of interest into a specific cell type is an essential aspect of biomedical research. Viruses can be a useful tool for this delivery, particularly in difficult to transfect cell types. Adeno-associated virus (AAV) is a useful gene transfer vector because of i...

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Detalles Bibliográficos
Autores principales: Ellis, Brian L, Hirsch, Matthew L, Barker, Jenny C, Connelly, Jon P, Steininger, Robert J, Porteus, Matthew H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607841/
https://www.ncbi.nlm.nih.gov/pubmed/23497173
http://dx.doi.org/10.1186/1743-422X-10-74