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Bone morphogenetic proteins enhance an epithelial-mesenchymal transition in normal airway epithelial cells during restitution of a disrupted epithelium

BACKGROUND: Mechanisms of airway repair are poorly understood. It has been proposed that, following injury, progenitor populations such as club cells (Clara) become undifferentiated, proliferate and re-differentiate to re-epithelialise the airway. The exact phenotype of such cells during repair is u...

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Detalles Bibliográficos
Autores principales: McCormack, Natasha, Molloy, Emer L, O’Dea, Shirley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607850/
https://www.ncbi.nlm.nih.gov/pubmed/23509993
http://dx.doi.org/10.1186/1465-9921-14-36