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Prevalence of antifolate resistance mutations in Plasmodium falciparum isolates in Afghanistan

BACKGROUND: Artesunate plus sulphadoxine-pyrimethamine (AS+SP) is now first-line treatment for Plasmodium falciparum infection in several south Asian countries, including Afghanistan. Molecular studies provide a sensitive means to investigate the current state of drug susceptibility to the SP compon...

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Detalles Bibliográficos
Autores principales: Awab, Ghulam R, Pukrittayakamee, Sasithon, Jamornthanyawat, Natsuda, Yamin, Fazel, Dondorp, Arjen M, Day, Nicholas PJ, White, Nicholas J, Woodrow, Charles J, Imwong, Mallika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607912/
https://www.ncbi.nlm.nih.gov/pubmed/23497229
http://dx.doi.org/10.1186/1475-2875-12-96