Gene regulatory network analysis supports inflammation as a key neurodegeneration process in prion disease

BACKGROUND: The activation of immune cells in the brain is believed to be one of the earliest events in prion disease development, where misfolded PrionSc protein deposits are thought to act as irritants leading to a series of events that culminate in neuronal cell dysfunction and death. The role of...

Descripción completa

Detalles Bibliográficos
Autores principales: Crespo, Isaac, Roomp, Kirsten, Jurkowski, Wiktor, Kitano, Hiroaki, del Sol, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607922/
https://www.ncbi.nlm.nih.gov/pubmed/23068602
http://dx.doi.org/10.1186/1752-0509-6-132

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607922/
https://www.ncbi.nlm.nih.gov/pubmed/23068602
http://dx.doi.org/10.1186/1752-0509-6-132

Ejemplares similares