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Gene regulatory network analysis supports inflammation as a key neurodegeneration process in prion disease
BACKGROUND: The activation of immune cells in the brain is believed to be one of the earliest events in prion disease development, where misfolded PrionSc protein deposits are thought to act as irritants leading to a series of events that culminate in neuronal cell dysfunction and death. The role of...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607922/ https://www.ncbi.nlm.nih.gov/pubmed/23068602 http://dx.doi.org/10.1186/1752-0509-6-132 |