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Cell division promotes efficient retrotransposition in a stable L1 reporter cell line

BACKGROUND: Long interspersed element type one (L1) actively modifies the human genome by inserting new copies of itself. This process, termed retrotransposition, requires the formation of an L1 ribonucleoprotein (RNP) complex, which must enter the nucleus before retrotransposition can proceed. Thus...

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Detalles Bibliográficos
Autores principales: Xie, Yi, Mates, Lajos, Ivics, Zoltán, Izsvák, Zsuzsanna, Martin, Sandra L, An, Wenfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607998/
https://www.ncbi.nlm.nih.gov/pubmed/23497436
http://dx.doi.org/10.1186/1759-8753-4-10