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RET Gene Abnormalities and Thyroid Disease: Who Should be Screened and When

Mutations in the RET proto-oncogene have been implicated in the pathogenesis of several forms of medullary thyroid cancer (MTC). Multiple endocrine neoplasia type 2 (MEN-2) is an autosomal dominant syndrome caused by germline activating mutations of the RET proto-oncogene and has been categorized in...

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Detalles Bibliográficos
Autores principales: Salehian, Behrouz, Samoa, Raynald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608003/
https://www.ncbi.nlm.nih.gov/pubmed/23455356
http://dx.doi.org/10.4274/Jcrpe.870