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Alternative activation of macrophages by filarial nematodes is MyD88-independent

Alternative macrophage activation is largely defined by IL-4Rα stimulation but the contribution of Toll-like receptor (TLR) signaling to this phenotype is not currently known. We have investigated macrophage activation status under Th2 conditions in the absence of the core TLR adaptor molecule, MyD8...

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Detalles Bibliográficos
Autores principales: Mylonas, Katie J., Hoeve, Marieke A., MacDonald, Andrew S., Allen, Judith E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608026/
https://www.ncbi.nlm.nih.gov/pubmed/22884360
http://dx.doi.org/10.1016/j.imbio.2012.07.006