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Lessons learnt from the first efficacy trial of a new infant tuberculosis vaccine since BCG

BACKGROUND: New tuberculosis (TB) vaccines are being developed to combat the global epidemic. A phase IIb trial of a candidate vaccine, MVA85A, was conducted in a high burden setting in South Africa to evaluate proof-of-concept efficacy for prevention of TB in infants. OBJECTIVE: To describe the stu...

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Detalles Bibliográficos
Autores principales: Tameris, Michele, McShane, Helen, McClain, J. Bruce, Landry, Bernard, Lockhart, Stephen, Luabeya, Angelique K.K., Geldenhuys, Hennie, Shea, Jacqui, Hussey, Gregory, van der Merwe, Linda, de Kock, Marwou, Scriba, Thomas, Walker, Robert, Hanekom, Willem, Hatherill, Mark, Mahomed, Hassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Churchill Livingstone 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608032/
https://www.ncbi.nlm.nih.gov/pubmed/23410889
http://dx.doi.org/10.1016/j.tube.2013.01.003