Adaptive regulatory substitutions affect multiple stages in the life cycle of the bacteriophage ϕX174

BACKGROUND: Previously, we showed that adaptive substitutions in one of the three promoters of the bacteriophage ϕX174 improved fitness at high-temperature by decreasing transcript levels three- to four-fold. To understand how such an extreme change in gene expression might lead to an almost two-fol...

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Detalles Bibliográficos
Autores principales: Brown, Celeste J, Stancik, Amber D, Roychoudhury, Pavitra, Krone, Stephen M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608072/
https://www.ncbi.nlm.nih.gov/pubmed/23506096
http://dx.doi.org/10.1186/1471-2148-13-66

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608072/
https://www.ncbi.nlm.nih.gov/pubmed/23506096
http://dx.doi.org/10.1186/1471-2148-13-66

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