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patGPCR: A Multitemplate Approach for Improving 3D Structure Prediction of Transmembrane Helices of G-Protein-Coupled Receptors

The structures of the seven transmembrane helices of G-protein-coupled receptors are critically involved in many aspects of these receptors, such as receptor stability, ligand docking, and molecular function. Most of the previous multitemplate approaches have built a “super” template with very littl...

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Detalles Bibliográficos
Autores principales: Wu, Hongjie, Lü, Qiang, Quan, Lijun, Qian, Peide, Xia, Xiaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608176/
https://www.ncbi.nlm.nih.gov/pubmed/23554839
http://dx.doi.org/10.1155/2013/486125