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A Rab11a-Rab8a-Myo5B network promotes stretch-regulated exocytosis in bladder umbrella cells

Multiple Rabs are associated with secretory granules/vesicles, but how these GTPases are coordinated to promote regulated exocytosis is not well understood. In bladder umbrella cells a subapical pool of discoidal/fusiform-shaped vesicles (DFVs) undergoes Rab11a-dependent regulated exocytosis in resp...

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Detalles Bibliográficos
Autores principales: Khandelwal, Puneet, Prakasam, H. Sandeep, Clayton, Dennis R., Ruiz, Wily G., Gallo, Luciana I., van Roekel, Daniel, Lukianov, Stefan, Peränen, Johan, Goldenring, James R., Apodaca, Gerard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608489/
https://www.ncbi.nlm.nih.gov/pubmed/23389633
http://dx.doi.org/10.1091/mbc.E12-08-0568