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Evidence for dynein and astral microtubule–mediated cortical release and transport of Gα(i)/LGN/NuMA complex in mitotic cells

Spindle positioning is believed to be governed by the interaction between astral microtubules and the cell cortex and involve cortically anchored motor protein dynein. How dynein is recruited to and regulated at the cell cortex to generate forces on astral microtubules is not clear. Here we show tha...

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Detalles Bibliográficos
Autores principales: Zheng, Zhen, Wan, Qingwen, Liu, Jing, Zhu, Huabin, Chu, Xiaogang, Du, Quansheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608500/
https://www.ncbi.nlm.nih.gov/pubmed/23389635
http://dx.doi.org/10.1091/mbc.E12-06-0458