High-Throughput Carrier Screening Using TaqMan Allelic Discrimination

Members of the Ashkenazi Jewish community are at an increased risk for inheritance of numerous genetic diseases such that carrier screening is medically recommended. This paper describes the development and evaluation of 30 TaqMan allelic discrimination qPCR assays for 29 mutations on 2 different hi...

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Detalles Bibliográficos
Autores principales: Fedick, Anastasia, Su, Jing, Jalas, Chaim, Northrop, Lesley, Devkota, Batsal, Ekstein, Josef, Treff, Nathan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608587/
https://www.ncbi.nlm.nih.gov/pubmed/23555759
http://dx.doi.org/10.1371/journal.pone.0059722

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608587/
https://www.ncbi.nlm.nih.gov/pubmed/23555759
http://dx.doi.org/10.1371/journal.pone.0059722

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