Automated Universal BRAF State Detection within the Activation Segment in Skin Metastases by Pyrosequencing-Based Assay U-BRAF(V600)

Malignant melanoma is a highly-aggressive type of malignancy with considerable metastatic potential and frequent resistance to cytotoxic agents. BRAF mutant protein was recently recognized as therapeutic target in metastatic melanoma. We present a newly-developed U-BRAF(V600) approach – a universal...

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Detalles Bibliográficos
Autores principales: Skorokhod, Alexander, Helmbold, Peter, Brors, Benedikt, Schirmacher, Peter, Enk, Alexander, Penzel, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608589/
https://www.ncbi.nlm.nih.gov/pubmed/23555633
http://dx.doi.org/10.1371/journal.pone.0059221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608589/
https://www.ncbi.nlm.nih.gov/pubmed/23555633
http://dx.doi.org/10.1371/journal.pone.0059221

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