Cargando…

Non-Selective Calcium Channel Blocker Bepridil Decreases Secondary Pathology in Mice after Photothrombotic Cortical Lesion

Experimental studies have identified a complex link between neurodegeneration, β-amyloid (Aβ) and calcium homeostasis. Here we asked whether early phase β-amyloid pathology in transgenic hAPP(SL) mice exaggerates the ischemic lesion and remote secondary pathology in the thalamus, and whether a non-s...

Descripción completa

Detalles Bibliográficos
Autores principales: Lipsanen, Anu, Flunkert, Stefanie, Kuptsova, Kristina, Hiltunen, Mikko, Windisch, Manfred, Hutter-Paier, Birgit, Jolkkonen, Jukka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608597/
https://www.ncbi.nlm.nih.gov/pubmed/23555933
http://dx.doi.org/10.1371/journal.pone.0060235