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Non-Selective Calcium Channel Blocker Bepridil Decreases Secondary Pathology in Mice after Photothrombotic Cortical Lesion
Experimental studies have identified a complex link between neurodegeneration, β-amyloid (Aβ) and calcium homeostasis. Here we asked whether early phase β-amyloid pathology in transgenic hAPP(SL) mice exaggerates the ischemic lesion and remote secondary pathology in the thalamus, and whether a non-s...
Autores principales: | Lipsanen, Anu, Flunkert, Stefanie, Kuptsova, Kristina, Hiltunen, Mikko, Windisch, Manfred, Hutter-Paier, Birgit, Jolkkonen, Jukka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608597/ https://www.ncbi.nlm.nih.gov/pubmed/23555933 http://dx.doi.org/10.1371/journal.pone.0060235 |
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