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A Combination of Cytokines Rescues Highly Purified Leukemic CLL B-Cells from Spontaneous Apoptosis In Vitro

B-chronic lymphocytic leukemia (B-CLL), the most common human leukemia, is characterized by predominantly non-dividing malignant mature CD5+ B lymphocytes with an apoptosis defect. Various microenvironmental stimuli confer a growth advantage on these leukemic cells and extend their survival in vivo....

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Detalles Bibliográficos
Autores principales: Ghamlouch, Hussein, Ouled-Haddou, Hakim, Damaj, Gandhi, Royer, Bruno, Gubler, Brigitte, Marolleau, Jean-Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608602/
https://www.ncbi.nlm.nih.gov/pubmed/23555960
http://dx.doi.org/10.1371/journal.pone.0060370