Gene Mutation in MicroRNA Target Sites of CFTR Gene: A Novel Pathogenetic Mechanism in Cystic Fibrosis?

Cystic fibrosis (CF) is the most frequent lethal genetic disorder among Caucasians. It depends on alterations of a chloride channel expressed by most epithelial cells and encoded by CFTR gene. Also using scanning techniques to analyze the whole coding regions of CFTR gene, mutations are not identifi...

Descripción completa

Detalles Bibliográficos
Autores principales: Amato, Felice, Seia, Manuela, Giordano, Sonia, Elce, Ausilia, Zarrilli, Federica, Castaldo, Giuseppe, Tomaiuolo, Rossella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608608/
https://www.ncbi.nlm.nih.gov/pubmed/23555973
http://dx.doi.org/10.1371/journal.pone.0060448

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608608/
https://www.ncbi.nlm.nih.gov/pubmed/23555973
http://dx.doi.org/10.1371/journal.pone.0060448

Ejemplares similares