IRSp53 Mediates Podosome Formation via VASP in NIH-Src Cells

Podosomes are cellular “feet,” characterized by F-actin-rich membrane protrusions, which drive cell migration and invasion into the extracellular matrix. Small GTPases that regulate the actin cytoskeleton, such as Cdc42 and Rac are central regulators of podosome formation. The adaptor protein IRSp53...

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Detalles Bibliográficos
Autores principales: Oikawa, Tsukasa, Okamura, Hitomi, Dietrich, Franziska, Senju, Yosuke, Takenawa, Tadaomi, Suetsugu, Shiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608619/
https://www.ncbi.nlm.nih.gov/pubmed/23555988
http://dx.doi.org/10.1371/journal.pone.0060528

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608619/
https://www.ncbi.nlm.nih.gov/pubmed/23555988
http://dx.doi.org/10.1371/journal.pone.0060528

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