A Systematic In Silico Search for Target Similarity Identifies Several Approved Drugs with Potential Activity against the Plasmodium falciparum Apicoplast

Most of the drugs in use against Plasmodium falciparum share similar modes of action and, consequently, there is a need to identify alternative potential drug targets. Here, we focus on the apicoplast, a malarial plastid-like organelle of algal source which evolved through secondary endosymbiosis. W...

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Detalles Bibliográficos
Autores principales: Bispo, Nadlla Alves, Culleton, Richard, Silva, Lourival Almeida, Cravo, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608639/
https://www.ncbi.nlm.nih.gov/pubmed/23555651
http://dx.doi.org/10.1371/journal.pone.0059288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608639/
https://www.ncbi.nlm.nih.gov/pubmed/23555651
http://dx.doi.org/10.1371/journal.pone.0059288

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