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Single Residues in the Outer Pore of TRPV1 and TRPV3 Have Temperature-Dependent Conformations

Thermosensation is mediated by ion channels that are highly temperature-sensitive. Several members of the family of transient receptor potential (TRP) ion channels are activated by cold or hot temperatures and have been shown to function as temperature sensors in vivo. The molecular mechanism of tem...

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Detalles Bibliográficos
Autores principales: Kim, Sung Eun, Patapoutian, Ardem, Grandl, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608658/
https://www.ncbi.nlm.nih.gov/pubmed/23555720
http://dx.doi.org/10.1371/journal.pone.0059593