Oxidative Stress Induces Monocyte Necrosis with Enrichment of Cell-Bound Albumin and Overexpression of Endoplasmic Reticulum and Mitochondrial Chaperones

In the present study, monocytes were treated with 5-azacytidine (azacytidine), gossypol or hydrogen peroxide to induce cell death through oxidative stress. A shift from apoptotic to necrotic cell death occurred when monocytes were treated with 100 µM azacytidine for more than 12 hours. Necrotic mono...

Descripción completa

Detalles Bibliográficos
Autores principales: Tang, Haiping, Tian, Enbing, Liu, Chongdong, Wang, Qingtao, Deng, Haiteng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608663/
https://www.ncbi.nlm.nih.gov/pubmed/23555724
http://dx.doi.org/10.1371/journal.pone.0059610

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608663/
https://www.ncbi.nlm.nih.gov/pubmed/23555724
http://dx.doi.org/10.1371/journal.pone.0059610

Ejemplares similares