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Odorant Metabolism Catalyzed by Olfactory Mucosal Enzymes Influences Peripheral Olfactory Responses in Rats

A large set of xenobiotic-metabolizing enzymes (XMEs), such as the cytochrome P450 monooxygenases (CYPs), esterases and transferases, are highly expressed in mammalian olfactory mucosa (OM). These enzymes are known to catalyze the biotransformation of exogenous compounds to facilitate elimination. H...

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Detalles Bibliográficos
Autores principales: Thiebaud, Nicolas, Veloso Da Silva, Stéphanie, Jakob, Ingrid, Sicard, Gilles, Chevalier, Joëlle, Ménétrier, Franck, Berdeaux, Olivier, Artur, Yves, Heydel, Jean-Marie, Le Bon, Anne-Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608737/
https://www.ncbi.nlm.nih.gov/pubmed/23555703
http://dx.doi.org/10.1371/journal.pone.0059547