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Odorant Metabolism Catalyzed by Olfactory Mucosal Enzymes Influences Peripheral Olfactory Responses in Rats
A large set of xenobiotic-metabolizing enzymes (XMEs), such as the cytochrome P450 monooxygenases (CYPs), esterases and transferases, are highly expressed in mammalian olfactory mucosa (OM). These enzymes are known to catalyze the biotransformation of exogenous compounds to facilitate elimination. H...
Autores principales: | Thiebaud, Nicolas, Veloso Da Silva, Stéphanie, Jakob, Ingrid, Sicard, Gilles, Chevalier, Joëlle, Ménétrier, Franck, Berdeaux, Olivier, Artur, Yves, Heydel, Jean-Marie, Le Bon, Anne-Marie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608737/ https://www.ncbi.nlm.nih.gov/pubmed/23555703 http://dx.doi.org/10.1371/journal.pone.0059547 |
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