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Microbiologically active Mannich bases derived from 1,2,4-triazoles. The effect of C-5 substituent on antibacterial activity

Our research proved that chemical character of the C-5 substituent significantly determines the antibacterial activity of the Mannich bases derived from 4,5-disubstituted 1,2,4-triazole-3-thiones. This activity was considerably increased by an introduction of a chlorine atom to the phenyl ring. The...

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Detalles Bibliográficos
Autores principales: Plech, Tomasz, Wujec, Monika, Majewska, Magdalena, Kosikowska, Urszula, Malm, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608860/
https://www.ncbi.nlm.nih.gov/pubmed/23543889
http://dx.doi.org/10.1007/s00044-012-0248-y