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An Open-Label Investigation of the Pharmacokinetic Profiles of Lisdexamfetamine Dimesylate and Venlafaxine Extended-Release, Administered Alone and in Combination, in Healthy Adults

BACKGROUND: Lisdexamfetamine dimesylate (LDX), a prodrug consisting of d-amphetamine and l-lysine, is being studied in clinical trials of major depressive disorder. Additional drug-drug interaction studies were warranted. OBJECTIVE: This study aimed to describe the pharmacokinetics and safety of LDX...

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Detalles Bibliográficos
Autores principales: Ermer, James, Haffey, Mary B., Richards, Cynthia, Lasseter, Kenneth, Roesch, Benno, Purkayastha, Jaideep, Corcoran, Mary, Harlin, Bree, Martin, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing AG 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608883/
https://www.ncbi.nlm.nih.gov/pubmed/23512639
http://dx.doi.org/10.1007/s40261-013-0073-1