Stress hormones promote growth of B16-F10 melanoma metastases: an interleukin 6- and glutathione-dependent mechanism

BACKGROUND: Interleukin (IL)-6 (mainly of tumor origin) activates glutathione (GSH) release from hepatocytes and its interorgan transport to B16-F10 melanoma metastatic foci. We studied if this capacity to overproduce IL-6 is regulated by cancer cell-independent mechanisms. METHODS: Murine B16-F10 m...

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Detalles Bibliográficos
Autores principales: Valles, Soraya L, Benlloch, María, Rodriguez, María L, Mena, Salvador, Pellicer, José A, Asensi, Miguel, Obrador, Elena, Estrela, José M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608962/
https://www.ncbi.nlm.nih.gov/pubmed/23517603
http://dx.doi.org/10.1186/1479-5876-11-72

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608962/
https://www.ncbi.nlm.nih.gov/pubmed/23517603
http://dx.doi.org/10.1186/1479-5876-11-72

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