Cargando…

Stress hormones promote growth of B16-F10 melanoma metastases: an interleukin 6- and glutathione-dependent mechanism

BACKGROUND: Interleukin (IL)-6 (mainly of tumor origin) activates glutathione (GSH) release from hepatocytes and its interorgan transport to B16-F10 melanoma metastatic foci. We studied if this capacity to overproduce IL-6 is regulated by cancer cell-independent mechanisms. METHODS: Murine B16-F10 m...

Descripción completa

Detalles Bibliográficos
Autores principales:	Valles, Soraya L, Benlloch, María, Rodriguez, María L, Mena, Salvador, Pellicer, José A, Asensi, Miguel, Obrador, Elena, Estrela, José M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608962/ https://www.ncbi.nlm.nih.gov/pubmed/23517603 http://dx.doi.org/10.1186/1479-5876-11-72

Ejemplares similares

Glucocorticoid Receptor Knockdown Decreases the Antioxidant Protection of B16 Melanoma Cells: An Endocrine System-Related Mechanism that Compromises Metastatic Cell Resistance to Vascular Endothelium-Induced Tumor Cytotoxicity
por: Obrador, Elena, et al.
Publicado: (2014)

Glutathione and Bcl-2 targeting facilitates elimination by chemoradiotherapy of human A375 melanoma xenografts overexpressing bcl-xl, bcl-2, and mcl-1
por: Mena, Salvador, et al.
Publicado: (2012)

Pterostilbene Decreases the Antioxidant Defenses of Aggressive Cancer Cells In Vivo: A Physiological Glucocorticoids- and Nrf2-Dependent Mechanism
por: Benlloch, María, et al.
Publicado: (2016)

An Intercellular Flow of Glutathione Regulated by Interleukin 6 Links Astrocytes and the Liver in the Pathophysiology of Amyotrophic Lateral Sclerosis
por: López-Blanch, Rafael, et al.
Publicado: (2021)

Glutathione in Cancer Cell Death
por: Ortega, Angel L., et al.
Publicado: (2011)

Oxidative Stress, Neuroinflammation and Mitochondria in the Pathophysiology of Amyotrophic Lateral Sclerosis
por: Obrador, Elena, et al.
Publicado: (2020)

The Link between Oxidative Stress, Redox Status, Bioenergetics and Mitochondria in the Pathophysiology of ALS
por: Obrador, Elena, et al.
Publicado: (2021)

N-Acetylcysteine Promotes Metastatic Spread of Melanoma in Mice
por: Obrador, Elena, et al.
Publicado: (2022)

Survival Mechanisms of Metastatic Melanoma Cells: The Link between Glucocorticoids and the Nrf2-Dependent Antioxidant Defense System
por: Obrador, Elena, et al.
Publicado: (2023)

Role of Natural Stilbenes in the Prevention of Cancer
por: Sirerol, J. Antoni, et al.
Publicado: (2016)

Nuclear and Radiological Emergencies: Biological Effects, Countermeasures and Biodosimetry
por: Obrador, Elena, et al.
Publicado: (2022)

Combination of natural polyphenols with a precursor of NAD(+) and a TLR2/6 ligand lipopeptide protects mice against lethal γ radiation
por: Obrador, Elena, et al.
Publicado: (2022)

Oxidative and Nitrosative Stress in the Metastatic Microenvironment
por: Ortega, Ángel L., et al.
Publicado: (2010)

Radioprotection and Radiomitigation: From the Bench to Clinical Practice
por: Obrador, Elena, et al.
Publicado: (2020)

NAD(+) Precursors and Antioxidants for the Treatment of Amyotrophic Lateral Sclerosis
por: Obrador, Elena, et al.
Publicado: (2021)

The effect of combined expression of interleukin 2 and interleukin 4 on the tumorigenicity and treatment of B16F10 melanoma.
por: Hollingsworth, S. J., et al.
Publicado: (1996)

Effect of Rosmarinic Acid and Ionizing Radiation on Glutathione in Melanoma B16F10 Cells: A Translational Opportunity
por: Olivares, Amparo, et al.
Publicado: (2020)

Pterostilbene-Induced Tumor Cytotoxicity: A Lysosomal Membrane Permeabilization-Dependent Mechanism
por: Mena, Salvador, et al.
Publicado: (2012)

WIN 55,212-2, Agonist of Cannabinoid Receptors, Prevents Amyloid β(1-42) Effects on Astrocytes in Primary Culture
por: Aguirre-Rueda, Diana, et al.
Publicado: (2015)

Sugammadex, a Neuromuscular Blockade Reversal Agent, Causes Neuronal Apoptosis in Primary Cultures
por: Palanca, José M., et al.
Publicado: (2013)

Acute and Long-Term Effects of Hyperthermia in B16-F10 Melanoma Cells
por: Garcia, Mónica Pereira, et al.
Publicado: (2012)

Phase II trial of intralesional therapy with interleukin-2 in soft-tissue melanoma metastases
por: Radny, P, et al.
Publicado: (2003)

Astrocytes Protect Neurons from Aβ(1-42) Peptide-Induced Neurotoxicity Increasing TFAM and PGC-1 and Decreasing PPAR-γ and SIRT-1
por: Aguirre-Rueda, Diana, et al.
Publicado: (2015)

The fatty acid synthase inhibitor orlistat reduces experimental metastases and angiogenesis in B16-F10 melanomas
por: Seguin, F, et al.
Publicado: (2012)

Poor Bone Quality in Patients With Amyotrophic Lateral Sclerosis
por: Caplliure-Llopis, Jordi, et al.
Publicado: (2020)

Pterostilbene in Cancer Therapy
por: Obrador, Elena, et al.
Publicado: (2021)

MALIGNANT MELANOMA – CUTANEOUS METASTASES
por: Padmavathy, L, et al.
Publicado: (2008)

Externally Applied Electromagnetic Fields and Hyperthermia Irreversibly Damage Cancer Cells
por: Obrador, Elena, et al.
Publicado: (2023)

Low-dose inhalation of interleukin-2 bio-chemotherapy for the treatment of pulmonary metastases in melanoma patients
por: Posch, C, et al.
Publicado: (2014)

Facilitation of Insulin Effects by Ranolazine in Astrocytes in Primary Culture
por: Jordá, Adrián, et al.
Publicado: (2022)

Melanoma metastases caught in the AKT
por: Kircher, David A., et al.
Publicado: (2016)

Changes in Chemokines and Chemokine Receptors Expression in a Mouse Model of Alzheimer's Disease
por: Jorda, Adrián, et al.
Publicado: (2019)

Melanoma with gastric metastases
por: Wong, Katherine, et al.
Publicado: (2016)

Unusual metastases of melanoma
por: Carillio, Guido, et al.
Publicado: (2018)

Effects of Ranolazine on Astrocytes and Neurons in Primary Culture
por: Aldasoro, Martin, et al.
Publicado: (2016)

Neuronal Effects of Sugammadex in combination with Rocuronium or Vecuronium
por: Aldasoro, Martin, et al.
Publicado: (2017)

Interleukins in the treatment of melanoma
por: Xu, Xinyuan, et al.
Publicado: (2022)

Metabolomics Reveals the Alteration of Metabolic Pathway by Alpha-Melanocyte-Stimulating Hormone in B16F10 Melanoma Cells
por: Seo, Seung-Ho, et al.
Publicado: (2020)

Gamma knife radiosurgery for the treatment of uveal melanoma and uveal metastases
por: Reynolds, Margaret M., et al.
Publicado: (2017)

Downregulation of adaptor protein MyD88 compromises the angiogenic potential of B16 murine melanoma
por: Trucco, Lucas Daniel, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_6lha584m6os8o1lqhsc1feq648