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BDNF regulates atypical PKC at spinal synapses to initiate and maintain a centralized chronic pain state
BACKGROUND: Chronic pain is an important medical problem affecting hundreds of millions of people worldwide. Mechanisms underlying the maintenance of chronic pain states are poorly understood but the elucidation of such mechanisms have the potential to reveal novel therapeutics capable of reversing...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608966/ https://www.ncbi.nlm.nih.gov/pubmed/23510079 http://dx.doi.org/10.1186/1744-8069-9-12 |