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Detection and characterization of classical and “uncommon” exon 19 Epidermal Growth Factor Receptor mutations in lung cancer by pyrosequencing

BACKGROUND: The management of advanced stage non-small cell lung cancer is increasingly based on diagnostic and predictive analyses performed mostly on limited amounts of tumor tissue. The evaluation of Epidermal Growth Factor Receptor (EGFR) mutations have emerged as the strongest predictor of resp...

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Detalles Bibliográficos
Autores principales: Righi, Luisella, Cuccurullo, Alessandra, Vatrano, Simona, Cappia, Susanna, Giachino, Daniela, Giuli, Paolo De, Ardine, Mara, Novello, Silvia, Volante, Marco, Scagliotti, Giorgio V, Papotti, Mauro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608975/
https://www.ncbi.nlm.nih.gov/pubmed/23497146
http://dx.doi.org/10.1186/1471-2407-13-114