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Prions, prionoids and pathogenic proteins in Alzheimer disease

Like patients with prion disease, Alzheimer patients suffer from a fatal, progressive form of dementia. There is growing evidence that amyloid-β (Aβ) aggregates may be transmissible similar to prions, at least under extreme experimental conditions. However, unlike mice infected with prion protein (P...

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Detalles Bibliográficos
Autores principales: Ashe, Karen H., Aguzzi, Adriano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609051/
https://www.ncbi.nlm.nih.gov/pubmed/23208281
http://dx.doi.org/10.4161/pri.23061