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Prion pathogenesis and secondary lymphoid organs (SLO): Tracking the SLO spread of prions to the brain
Prion diseases are subacute neurodegenerative diseases that affect humans and a range of domestic and free-ranging animal species. These diseases are characterized by the accumulation of PrP(Sc), an abnormally folded isoform of the cellular prion protein (PrP(C)), in affected tissues. The pathology...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Landes Bioscience
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609058/ https://www.ncbi.nlm.nih.gov/pubmed/22895090 http://dx.doi.org/10.4161/pri.20676 |