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Comparison of the local structural stabilities of mammalian prion protein (PrP) by fragment molecular orbital calculations

Bovine spongiform encephalopathy (BSE), a member of the prion diseases, is a fatal neurodegenerative disorder suspected to be caused by a malfunction of prion protein (PrP). Although BSE prions have been reported to be transmitted to a wide range of animal species, dogs and hamsters are known to be...

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Detalles Bibliográficos
Autores principales: Hasegawa, Koji, Mohri, Shirou, Yokoyama, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609128/
https://www.ncbi.nlm.nih.gov/pubmed/23232497
http://dx.doi.org/10.4161/pri.23122