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A closer look at prion strains: Characterization and important implications

Prions are infectious proteins that are responsible for transmissible spongiform encephalopathies (TSEs) and consist primarily of scrapie prion protein (PrP(Sc)), a pathogenic isoform of the host-encoded cellular prion protein (PrP(C)). The absence of nucleic acids as essential components of the inf...

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Detalles Bibliográficos
Autores principales: Solforosi, Laura, Milani, Michela, Mancini, Nicasio, Clementi, Massimo, Burioni, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609129/
https://www.ncbi.nlm.nih.gov/pubmed/23357828
http://dx.doi.org/10.4161/pri.23490