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Sexually Dimorphic Effects of Maternal Nutrient Reduction on Expression of Genes Regulating Cortisol Metabolism in Fetal Baboon Adipose and Liver Tissues

Maternal nutrient reduction (MNR) during fetal development may predispose offspring to chronic disease later in life. Increased regeneration of active glucocorticoids by 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) in metabolic tissues is fundamental to the developmental programming of metabol...

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Detalles Bibliográficos
Autores principales: Guo, Chunming, Li, Cun, Myatt, Leslie, Nathanielsz, Peter W., Sun, Kang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609578/
https://www.ncbi.nlm.nih.gov/pubmed/23238295
http://dx.doi.org/10.2337/db12-0561