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Increase of Palmitic Acid Concentration Impairs Endothelial Progenitor Cell and Bone Marrow–Derived Progenitor Cell Bioavailability: Role of the STAT5/PPARγ Transcriptional Complex

Metabolic profiling of plasma nonesterified fatty acids discovered that palmitic acid (PA), a natural peroxisome proliferator–activated receptor γ (PPARγ) ligand, is a reliable type 2 diabetes biomarker. We investigated whether and how PA diabetic (d-PA) concentrations affected endothelial progenito...

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Detalles Bibliográficos
Autores principales: Trombetta, Antonella, Togliatto, Gabriele, Rosso, Arturo, Dentelli, Patrizia, Olgasi, Cristina, Cotogni, Paolo, Brizzi, Maria Felice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609587/
https://www.ncbi.nlm.nih.gov/pubmed/23223023
http://dx.doi.org/10.2337/db12-0646