HLA-A*24 Is an Independent Predictor of 5-Year Progression to Diabetes in Autoantibody-Positive First-Degree Relatives of Type 1 Diabetic Patients

We investigated whether HLA-A*24 typing complements screening for HLA-DQ and for antibodies (Abs) against insulin, GAD, IA-2 (IA-2A), and zinc transporter-8 (ZnT8A) for prediction of rapid progression to type 1 diabetes (T1D). Persistently Ab(+) siblings/offspring (n = 288; aged 0–39 years) of T1D p...

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Detalles Bibliográficos
Autores principales: Mbunwe, Eric, Van der Auwera, Bart J., Vermeulen, Ilse, Demeester, Simke, Van Dalem, Annelien, Balti, Eric V., Van Aken, Sara, Derdelinckx, Luc, Dorchy, Harry, De Schepper, Jean, van Schravendijk, Chris, Wenzlau, Janet M., Hutton, John C., Pipeleers, Daniël, Weets, Ilse, Gorus, Frans K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609594/
https://www.ncbi.nlm.nih.gov/pubmed/23160529
http://dx.doi.org/10.2337/db12-0747

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609594/
https://www.ncbi.nlm.nih.gov/pubmed/23160529
http://dx.doi.org/10.2337/db12-0747

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