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The Tyrosine Kinase Btk Regulates the Macrophage Response to Listeria monocytogenes Infection

In this study we investigated the role of Bruton's tyrosine kinase (Btk) in the immune response to the Gram-positive intracellular bacterium Listeria monocytogenes (Lm). In response to Lm infection, Btk was activated in bone marrow-derived macrophages (BMMs) and Btk (−/−) BMMs showed enhanced T...

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Detalles Bibliográficos
Autores principales: Köprülü, Afitap Derya, Kastner, Renate, Wienerroither, Sebastian, Lassnig, Caroline, Putz, Eva Maria, Majer, Olivia, Reutterer, Benjamin, Sexl, Veronika, Kuchler, Karl, Müller, Mathias, Decker, Thomas, Ellmeier, Wilfried
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609758/
https://www.ncbi.nlm.nih.gov/pubmed/23544144
http://dx.doi.org/10.1371/journal.pone.0060476