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Chito-Oligosaccharide Inhibits the De-Methylation of a ‘CpG’ Island within the Leptin (LEP) Promoter during Adipogenesis of 3T3-L1 Cells

Chito-oligosaccharide (COS) is a natural bioactive compound, which has been shown to suppress lipid metabolic genes and lipid accumulation in differentiating adipocytes. Leptin has been identified as a key regulator of energy homeostasis and is known to be under epigenetic regulation during adipogen...

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Detalles Bibliográficos
Autores principales: Bahar, Bojlul, O’Doherty, John V., O’Doherty, Alan M., Sweeney, Torres
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609775/
https://www.ncbi.nlm.nih.gov/pubmed/23544120
http://dx.doi.org/10.1371/journal.pone.0060011