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Doxycycline-Regulated 3T3-L1 Preadipocyte Cell Line with Inducible, Stable Expression of Adenoviral E4orf1 Gene: A Cell Model to Study Insulin-Independent Glucose Disposal

Impaired glycemic control and excessive adiposity are major risk factors for Type 2 Diabetes mellitus. In rodent models, Ad36, a human adenovirus, improves glycemic control, independent of dietary fat intake or adiposity. It is impractical to use Ad36 for therapeutic action. Instead, we identified t...

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Detalles Bibliográficos
Autores principales: Krishnapuram, Rashmi, Dhurandhar, Emily J., Dubuisson, Olga, Hegde, Vijay, Dhurandhar, Nikhil V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609787/
https://www.ncbi.nlm.nih.gov/pubmed/23544159
http://dx.doi.org/10.1371/journal.pone.0060651