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Transcriptional Instability during Evolving Sepsis May Limit Biomarker Based Risk Stratification

BACKGROUND: Sepsis causes extensive morbidity and mortality in children worldwide. Prompt recognition and timely treatment of sepsis is critical in reducing morbidity and mortality. Genomic approaches are used to discover novel pathways, therapeutic targets and biomarkers. These may facilitate diagn...

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Detalles Bibliográficos
Autores principales: Kwan, Antonia, Hubank, Mike, Rashid, Asrar, Klein, Nigel, Peters, Mark J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609793/
https://www.ncbi.nlm.nih.gov/pubmed/23544148
http://dx.doi.org/10.1371/journal.pone.0060501